Science

Publications:

Docosahexaenoic Acid Monoacylglyceride Decreases Endothelin-1 Induced Ca2+ Sensitivity and Proliferation in Human Pulmonary Arteries.  American Journal of Hypertension , (26 April 2012).

New Omega-3 Derivative Reduce Airway Inflammation and Prevent Rho-Kinase Activation in an Allergic Model of Asthma. J Aller Ther 2012, 2155-6121. S1-003

Bronchial inflammation induced PKCζ over-expression: involvement in mechanical
properties of airway smooth muscle. Canadian Journal of Physiology and Pharmacology, Published on the web 10 February 2012, 10.1139/y11-117

ω3 and ω6 CYP450 Eicosanoid Derivatives: Key Lipid Mediators in the Regulation of Pulmonary Hypertension Book Chapter in Pulmonary Hypertension – From Bench Research to Clinical Challenges ISBN 978-953-307-835-9, 2011.

19,20-EpDPE, a bioactive CYP450 metabolite of DHA monoacyglyceride, decreases Ca2+ sensitivity in human pulmonary arteries.  Am J Physiol Heart Circ Physiol, October 2011, 301:(4) H1311-H1318

DHA derivative prevents inflammation and hyperreactivity in lung: implication of CPI-17 in asthma AJRCMB 2011; Vol. 45: pp.366-375

 

Patents:

Canada

“POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF” CA2672513 Granted

“COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF”  CA2677670 Granted

United States

“POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF”  US20090292019 Granted

“COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF”  US20090291102

“POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF”  US20100160261

“COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF”  US20100196496

Europe

“POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF” EP20080714624

“COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF”  EP20080733634

India and Australia

“POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF”

“COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF”

 

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